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Geistlich Mucograft®

User Benefits

Geistlich Mucograft® is a collagen matrix designed specifically for soft-tissue regeneration in the oral cavity1. It is indicated for gaining keratinized tissue2,3,4  and for recession coverage5,6.

Geistlich Mucograft® provides an alternative to autologous soft-tissue grafts2,4,5,6. Painful harvesting of tissue is avoided, benefiting patients and clinicians alike.

Leading clinicians rely on Geistlich Mucograft®:

  • No harvest-site morbidity2,3,5-7.
  • Less pain compared with autologous grafts2,4.
  • Reduced surgical chair-time compared with autologous grafts2-6.
  • Natural soft-tissue colour and texture match5,8,9.
  • Early vascularization and good soft-tissue ingrowth10,11.
  • Good wound healing, also in open situations2.
  • Easy handling2 and application in a dry state.

Geistlich Mucograft® consists of two structures: the compact structure provides stability while allowing open healing; the spongy structure supports blood clot stabilization and ingrowth of soft-tissue cells.


  1. Biocompatibility according to ISO 10993-1. Data on file, Geistlich Pharma AG, Wolhusen, Switzerland.
  2. Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76. (clinical study)
  3. Konter U, et al.: Deutsche Zahnärztliche Zeitschrift 2010; 65: 723-30. (clinical study)
  4. Lorenzo R, et al.: Clin Oral Impl Res 2012; 23(3): 316-24. (clinical study)
  5. McGuire MK & Scheyer ET: J Periodontol 2010; 81(8): 1108-17. (clinical study)
  6. Cardaropoli D, et al.: J Periodontol 2012; 83(3): 321-28. (clinical study)
  7. Herford AS, et al.: J Oral Maxillofac Surg 2010; 68(7): 1463-70. (clinical study)
  8. Thoma, D, et al.: J Clin Periodontol 2012; 39(2): 157-65. (clinical study)
  9. Nevins M, et al.: Int J Periodontics Restorative Dent 2011; 31(4): 367-73. (clinical study)
  10. Ghanaati S, et al.: Biomed Mater. 2011 Feb; 6(1): 015010. (pre-clinical study)
  11. Rocchietta I, et al.: Int J Periodontics Restorative Dent. 2012; 32(1): e34-40. (pre-clinical study)

* Mucograft® (prototype) exhibited highly similar physical, mechanical and biological properties to the final product Geistlich Mucograft® differing only in the porcine collagen source used.


Geistlich Mucograft®

Geistlich Mucograft® is easy to handle compared with autologous soft-tissue grafts1:

  • Unlimited availability and consistent quality.
  • No need for pre-treatment or pre-hydration.
  • Measure the defect and trim the matrix to the required shape.
  • Apply the dry Geistlich Mucograft® to the defect; it will moisten rapidly due to marked hydrophilicity.
  • Position the compact structure facing outwards and the spongy structure towards the bone or periosteum.
  • Soaked matrix adapts spontaneously to contours and adheres well to defect.
  • The compact structure provides optimal suture pull-out strength.


  1. Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76. (clinical study)
  2. Abundo R & Corrente G: Chirurgia plastica parodontale – Trattamento estetico delle recessioni gengivali. ACME Edizioni, 2010. (book, clinical)

Product Range

Geistlich Mucograft® consists of porcine collagen and is specifically designed for soft-tissue regeneration. The matrix is available in three sizes:

Treatment concepts – Geistlich Mucograft® & Geistlich Mucograft Seal®